A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis

DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins. Here, we identify xNuRD, an MTA2-containing assemblage of the nucleosome remodeling and his...

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Detalles Bibliográficos
Autores principales: Christov, Christo P., Dingwell, Kevin S., Skehel, Mark, Wilkes, Helen S., Sale, Julian E., Smith, James C., Krude, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848848/
https://www.ncbi.nlm.nih.gov/pubmed/29490265
http://dx.doi.org/10.1016/j.celrep.2018.02.015

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