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Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway

Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of epithelial carcinomas, and it is involved in cell adhesion and proliferation. However, its expression profile and biological function in nasopharyngeal carcinoma (NPC) remains unclear. In this study, higher exp...

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Detalles Bibliográficos
Autores principales: Wang, Meng-He, Sun, Rui, Zhou, Xiao-Min, Zhang, Mei-Yin, Lu, Jia-Bin, Yang, Yang, Zeng, Li-Si, Yang, Xian-Zi, Shi, Lu, Xiao, Ruo-Wen, Wang, Hui-Yun, Mai, Shi-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849035/
https://www.ncbi.nlm.nih.gov/pubmed/29305578
http://dx.doi.org/10.1038/s41419-017-0013-8