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Intramolecular substitution uncages fluorogenic probes for detection of metallo-carbapenemase-expressing bacteria
This work reports a novel caging strategy for designing fluorogenic probes to detect the activity of β-lactamases. The caging strategy uses a thiophenyl linker connected to a fluorophore caged by a good leaving group—dinitrophenyl. The uncaging proceeds in two steps through the sulfa-releasing and s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849144/ https://www.ncbi.nlm.nih.gov/pubmed/29568429 http://dx.doi.org/10.1039/c7sc02416a |