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Reconstitution of high-grade serous ovarian carcinoma from primary fallopian tube secretory epithelial cells

Fallopian tube secretory epithelial cells (FTSECs) have been suggested to be the source of high-grade serous ovarian carcinoma (HGSOC). Although several genetic alterations are known to be involved in HGSOC development, the minimal requirements remain unclear. We aimed to identify oncogenic mutation...

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Detalles Bibliográficos
Autores principales: Nakamura, Kohei, Nakayama, Kentaro, Ishikawa, Noriyoshi, Ishikawa, Masako, Sultana, Razia, Kiyono, Tohru, Kyo, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849158/
https://www.ncbi.nlm.nih.gov/pubmed/29560094
http://dx.doi.org/10.18632/oncotarget.23035