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HCN channels contribute to the sensitivity of intravenous anesthetics in developmental mice

It is widely accepted that the induction dose of anesthetics is higher in infants than in adults, although the relevant molecular mechanism remains elusive. We previously showed neuronal hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels contribute to hypnotic actions of propofol an...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Hu, Zhiqiang, Shi, Liwei, Li, Na, Ouyang, Yeling, Shu, Shaofang, Yao, Shanglong, Chen, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849183/
https://www.ncbi.nlm.nih.gov/pubmed/29560119
http://dx.doi.org/10.18632/oncotarget.24408