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Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation

Hsa-miR-155-5p (miR-155) is overexpressed in most solid and hematological malignancies. It promotes loss of genomic integrity in cancer cells by targeting genes involved in microsatellite instability and DNA repair; however, the link between miR-155 and aneuploidy has been scarcely investigated. Her...

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Detalles Bibliográficos
Autores principales: Pagotto, Sara, Veronese, Angelo, Soranno, Alessandra, Lanuti, Paola, Di Marco, Mirco, Russo, Marco Vincenzo, Ramassone, Alice, Marchisio, Marco, Simeone, Pasquale, Guanciali Franchi, Paolo E., Palka, Giandomenico, Costantini, Renato Mariani, Croce, Carlo M., Visone, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849193/
https://www.ncbi.nlm.nih.gov/pubmed/29560129
http://dx.doi.org/10.18632/oncotarget.24437