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Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues

The selective killing of cancer cells and the avoidance of drug resistance are still difficult challenges in cancer therapy. Here, we report a new strategy that uses enzyme-induced gain of function (EIGF) to regulate the structure and function of phosphorylated melittin analogues (MelAs). Original M...

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Detalles Bibliográficos
Autores principales: Li, Qian-Qian, Chen, Pu-Guang, Hu, Zhi-Wen, Cao, Yuan, Chen, Liang-Xiao, Chen, Yong-Xiang, Zhao, Yu-Fen, Li, Yan-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849211/
https://www.ncbi.nlm.nih.gov/pubmed/29568430
http://dx.doi.org/10.1039/c7sc03217j