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Isolated Adrenocorticotropin Deficiency due to Nivolumab-induced Hypophysitis in a Patient with Advanced Lung Adenocarcinoma: A Case Report and Literature Review

A 63-year-old Japanese woman with advanced lung adenocarcinoma developed isolated adrenocorticotropin deficiency caused by immune checkpoint inhibitor (ICI)-related hypophysitis following 8 months of nivolumab therapy. Prompt corticosteroid replacement therapy effectively relieved her secondary adre...

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Detalles Bibliográficos
Autores principales: Ohara, Nobumasa, Ohashi, Kazumasa, Fujisaki, Toshiya, Oda, Chiyumi, Ikeda, Yohei, Yoneoka, Yuichiro, Hashimoto, Takehisa, Hasegawa, Go, Suzuki, Kazuo, Takada, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849549/
https://www.ncbi.nlm.nih.gov/pubmed/29151505
http://dx.doi.org/10.2169/internalmedicine.9074-17