Dual effect of PEG-PE micelle over the oligomerization and fibrillation of human islet amyloid polypeptide

The oligomerization and fibrillation of human islet amyloid polypeptide (hIAPP) play a central role in the pathogenesis of type 2 diabetes. Strategies for remodelling the formation of hIAPP oligomers and fibrils have promising application potential in type 2 diabetes therapy. Herein, we demonstrated...

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Detalles Bibliográficos
Autores principales: Fang, Xiaocui, Yousaf, Maryam, Huang, Qunxing, Yang, Yanlian, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849606/
https://www.ncbi.nlm.nih.gov/pubmed/29535385
http://dx.doi.org/10.1038/s41598-018-22820-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849606/
https://www.ncbi.nlm.nih.gov/pubmed/29535385
http://dx.doi.org/10.1038/s41598-018-22820-w

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