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Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination

The epidermis is a multi-layered epithelium that serves as a barrier against water loss and environmental insults. Its morphogenesis occurs through a tightly regulated program of biochemical and architectural changes during which basal cells commit to differentiate and move towards the skin’s surfac...

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Detalles Bibliográficos
Autores principales: Nekrasova, Oxana, Harmon, Robert M., Broussard, Joshua A., Koetsier, Jennifer L., Godsel, Lisa M., Fitz, Gillian N., Gardel, Margaret L., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849617/
https://www.ncbi.nlm.nih.gov/pubmed/29535305
http://dx.doi.org/10.1038/s41467-018-03414-6