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Clinical validation study of dried blood spot for determining everolimus concentration in patients with cancer

PURPOSE: Everolimus treatment is seriously hampered by its toxicity profile. As a relationship between everolimus exposure and effectiveness and toxicity has been established, early and ongoing concentration measurement can be key to individualize the dose and optimize treatment outcomes. Dried bloo...

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Detalles Bibliográficos
Autores principales: Willemsen, A. E. C. A. B., Knapen, L. M., de Beer, Y. M., Brüggemann, R. J. M., Croes, S., van Herpen, C. M. L., van Erp, N. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849667/
https://www.ncbi.nlm.nih.gov/pubmed/29222715
http://dx.doi.org/10.1007/s00228-017-2394-0