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Clinical validation study of dried blood spot for determining everolimus concentration in patients with cancer
PURPOSE: Everolimus treatment is seriously hampered by its toxicity profile. As a relationship between everolimus exposure and effectiveness and toxicity has been established, early and ongoing concentration measurement can be key to individualize the dose and optimize treatment outcomes. Dried bloo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849667/ https://www.ncbi.nlm.nih.gov/pubmed/29222715 http://dx.doi.org/10.1007/s00228-017-2394-0 |