Structure-based design of chimeric antigens for multivalent protein vaccines

There is an urgent need to develop vaccines against pathogenic bacteria. However, this is often hindered by antigenic diversity and difficulties encountered manufacturing membrane proteins. Here we show how to use structure-based design to develop chimeric antigens (ChAs) for subunit vaccines. ChAs...

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Detalles Bibliográficos
Autores principales: Hollingshead, S., Jongerius, I., Exley, R. M., Johnson, S., Lea, S. M., Tang, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849709/
https://www.ncbi.nlm.nih.gov/pubmed/29535307
http://dx.doi.org/10.1038/s41467-018-03146-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849709/
https://www.ncbi.nlm.nih.gov/pubmed/29535307
http://dx.doi.org/10.1038/s41467-018-03146-7

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