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Physiological activation of mGlu5 receptors supports the ion channel function of NMDA receptors in hippocampal LTD induction in vivo

Synaptic long-term depression (LTD) is believed to underlie critical mnemonic processes in the adult hippocampus. The roles of the metabotropic and ionotropic actions of glutamate in the induction of synaptic LTD by electrical low-frequency stimulation (LFS) in the living adult animal is poorly unde...

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Detalles Bibliográficos
Autores principales: O’Riordan, Kenneth J., Hu, Neng-Wei, Rowan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849730/
https://www.ncbi.nlm.nih.gov/pubmed/29535352
http://dx.doi.org/10.1038/s41598-018-22768-x