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Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro

Reversal of activated hepatic stellate cells (HSCs) to a quiescent state and apoptosis of activated HSCs are key elements in the reversion of hepatic fibrosis. CCAAT/enhancer binding protein α (C/EBP-α) has been shown to inhibit HSC activation and promote its apoptosis. This study aims to investigat...

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Detalles Bibliográficos
Autores principales: Ding, Di, Chen, Lin-Lin, Zhai, Ying-Zhen, Hou, Chen-Jian, Tao, Li-Li, Lu, Shu-Han, Wu, Jian, Liu, Xiu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849734/
https://www.ncbi.nlm.nih.gov/pubmed/29535398
http://dx.doi.org/10.1038/s41598-018-22662-6