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TGF-β1 promotes cell barrier function upon maturation of corneal endothelial cells

Human corneal endothelial cells (HCECs) easily become fibroblastic-like when cultured, rendering them unsuitable for tissue engineering of the cornea. Transforming growth factor β (TGF-β) could be a key factor in this phenomenon; however, TGF-β is also known to maintain the endothelium in a quiescen...

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Detalles Bibliográficos
Autores principales: Beaulieu Leclerc, Véronique, Roy, Olivier, Santerre, Kim, Proulx, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849742/
https://www.ncbi.nlm.nih.gov/pubmed/29535350
http://dx.doi.org/10.1038/s41598-018-22821-9