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Statistically derived asymmetric membrane potentials from α-helical and β-barrel membrane proteins

Modeling membrane protein (MP) folding, insertion, association and their interactions with other proteins, lipids, and drugs requires accurate transfer free energies (TFEs). Various TFE scales have been derived to quantify the energy required or released to insert an amino acid or protein into the m...

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Detalles Bibliográficos
Autores principales: Koehler Leman, Julia, Bonneau, Richard, Ulmschneider, Martin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849751/
https://www.ncbi.nlm.nih.gov/pubmed/29535329
http://dx.doi.org/10.1038/s41598-018-22476-6