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Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo
AIM: The aim of this study was to study the effect of celecoxib on agomelatine metabolism in vitro and in vivo. METHODS: Ten healthy male Sprague–Dawley rats were randomly divided into 2 groups: Group A (control group) and Group B (30 mg/kg celecoxib). Then a single dose of 20 mg/kg agomelatine was...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849912/ https://www.ncbi.nlm.nih.gov/pubmed/29563776 http://dx.doi.org/10.2147/DDDT.S160316 |