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Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo

AIM: The aim of this study was to study the effect of celecoxib on agomelatine metabolism in vitro and in vivo. METHODS: Ten healthy male Sprague–Dawley rats were randomly divided into 2 groups: Group A (control group) and Group B (30 mg/kg celecoxib). Then a single dose of 20 mg/kg agomelatine was...

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Detalles Bibliográficos
Autores principales:	He, Jiayang, Fang, Ping, Zheng, Xiang, Wang, Chenchen, Liu, Tenghui, Zhang, Bowen, Wen, Jian, Xu, Ren-ai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849912/ https://www.ncbi.nlm.nih.gov/pubmed/29563776 http://dx.doi.org/10.2147/DDDT.S160316

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