Mangiferin Improves Hepatic Lipid Metabolism Mainly Through Its Metabolite-Norathyriol by Modulating SIRT-1/AMPK/SREBP-1c Signaling

Objective: Mangiferin (MGF) is a natural xanthone, with regulation effect on lipid metabolism. However, the molecular mechanism remains unclear. We purposed after oral administration, MGF is converted to its active metabolite(s), which contributes to the effects on lipid metabolism. Methods: KK-A(y)...

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Detalles Bibliográficos
Autores principales: Li, Jian, Liu, Mengyang, Yu, Haiyang, Wang, Wei, Han, Lifeng, Chen, Qian, Ruan, Jingya, Wen, Shaoshi, Zhang, Yi, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850072/
https://www.ncbi.nlm.nih.gov/pubmed/29563875
http://dx.doi.org/10.3389/fphar.2018.00201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850072/
https://www.ncbi.nlm.nih.gov/pubmed/29563875
http://dx.doi.org/10.3389/fphar.2018.00201

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