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Using regulatory genomics data to interpret the function of disease variants and prioritise genes from expression studies
The identification of therapeutic targets is a critical step in the research and developement of new drugs, with several drug discovery programmes failing because of a weak linkage between target and disease. Genome-wide association studies and large-scale gene expression experiments are providing i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850119/ https://www.ncbi.nlm.nih.gov/pubmed/29568492 http://dx.doi.org/10.12688/f1000research.13577.2 |