A Disintegrin and Metalloprotease‐22 Attenuates Hypertrophic Remodeling in Mice Through Inhibition of the Protein Kinase B Signaling Pathway

BACKGROUND: Severe cardiac hypertrophy can lead to cardiac remodeling and even heart failure in the end, which is a leading cause of cardiovascular disease–related mortality worldwide. A disintegrin and metalloprotease‐22 (ADAM22), a member of the transmembrane and secreted metalloendopeptidase fami...

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Detalles Bibliográficos
Autores principales: Ren, Lingyun, Wu, Chuangyan, Yang, Kai, Chen, Shanshan, Ye, Ping, Wu, Jie, Zhang, Anchen, Huang, Xiaofan, Wang, Ke, Deng, Peng, Ding, Xiangchao, Chen, Manhua, Xia, Jiahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850139/
https://www.ncbi.nlm.nih.gov/pubmed/29358191
http://dx.doi.org/10.1161/JAHA.117.005696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850139/
https://www.ncbi.nlm.nih.gov/pubmed/29358191
http://dx.doi.org/10.1161/JAHA.117.005696

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