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Reduced N‐Type Ca(2+) Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis

BACKGROUND: Attenuated cardiac vagal activity is associated with ventricular arrhythmogenesis and related mortality in patients with chronic heart failure. Our recent study has shown that expression of N‐type Ca(2+) channel α‐subunits (Ca(v)2.2‐α) and N‐type Ca(2+) currents are reduced in intracardi...

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Detalles Bibliográficos
Autores principales: Zhang, Dongze, Tu, Huiyin, Cao, Liang, Zheng, Hong, Muelleman, Robert L., Wadman, Michael C., Li, Yu‐Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850164/
https://www.ncbi.nlm.nih.gov/pubmed/29335317
http://dx.doi.org/10.1161/JAHA.117.007457