Interaction Between the Sodium‐Glucose–Linked Transporter 2 Inhibitor Dapagliflozin and the Loop Diuretic Bumetanide in Normal Human Subjects

BACKGROUND: Dapagliflozin inhibits the sodium‐glucose–linked transporter 2 in the renal proximal tubule, thereby promoting glycosuria to reduce hyperglycemia in type 2 diabetes mellitus. Because these patients may require loop diuretics, and sodium‐glucose–linked transporter 2 inhibition causes an o...

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Detalles Bibliográficos
Autores principales: Wilcox, Christopher S., Shen, Wen, Boulton, David W., Leslie, Bruce R., Griffen, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850181/
https://www.ncbi.nlm.nih.gov/pubmed/29440005
http://dx.doi.org/10.1161/JAHA.117.007046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850181/
https://www.ncbi.nlm.nih.gov/pubmed/29440005
http://dx.doi.org/10.1161/JAHA.117.007046

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