Cargando…

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice

BACKGROUND: A disintegrin‐like metalloproteinase with thrombospondin motif type 1 member 13 (ADAMTS13), the von Willebrand factor–cleaving enzyme, decreases leukocyte and platelet recruitment and, thus, reduces thrombosis and inflammation. Recombinant human ADAMTS13 (rhADAMTS13) is a novel drug cand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Witsch, Thilo, Martinod, Kimberly, Sorvillo, Nicoletta, Portier, Irina, De Meyer, Simon F., Wagner, Denisa D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850234/ https://www.ncbi.nlm.nih.gov/pubmed/29367415 http://dx.doi.org/10.1161/JAHA.117.007004

Ejemplares similares

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
por: Zitomersky, Naamah L., et al.
Publicado: (2017)

Systemic antithrombotic effects of ADAMTS13
por: Chauhan, Anil K., et al.
Publicado: (2006)

Recombinant ADAMTS 13 in thrombotic thrombocytopenic purpura
por: Scully, Marie, et al.
Publicado: (2017)

Peptidylarginine deiminase 4 promotes age-related organ fibrosis
por: Martinod, Kimberly, et al.
Publicado: (2017)

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice
por: Hayashi, Hideki, et al.
Publicado: (2017)

ADAMTS13: a new link between thrombosis and inflammation
por: Chauhan, Anil K., et al.
Publicado: (2008)

Tissue Plasminogen Activator Neurotoxicity is Neutralized by Recombinant ADAMTS 13
por: Fan, Mengchen, et al.
Publicado: (2016)

Absence of exaggerated pharmacology by recombinant ADAMTS13 in the rat and monkey
por: Rossato, Paolo, et al.
Publicado: (2022)

Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia
por: Gao, Daniel, et al.
Publicado: (2023)

The role of ADAMTS13 in acute myocardial infarction: cause or consequence?
por: Eerenberg, Elise S., et al.
Publicado: (2016)

Characterization of biventricular alterations in myocardial (reverse) remodelling in aortic banding-induced chronic pressure overload
por: Miranda-Silva, Daniela, et al.
Publicado: (2019)

EGCG prevents pressure overload-induced myocardial remodeling by downregulating overexpression of HDAC5 in mice
por: Han, Xiao, et al.
Publicado: (2022)

ADAMTS13 and Non-ADAMTS13 Biomarkers in Immune-Mediated Thrombotic Thrombocytopenic Purpura
por: Bonnez, Quintijn, et al.
Publicado: (2023)

Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding
por: Vistnes, Maria, et al.
Publicado: (2014)

The role of androgens in pressure overload myocardial hypertrophy
por: Schafstedde, Marie, et al.
Publicado: (2023)

Differential Transcriptome Profile and Exercise Capacity in Cardiac Remodeling by Pressure Overload versus Volume Overload
por: Kim, Kyung-Hee, et al.
Publicado: (2019)

ADAMTS13, TTP and Beyond
por: Zheng, X Long
Publicado: (2012)

Disappearing acts of ADAMTS13
por: Voorberg, Jan, et al.
Publicado: (2015)

Mechanisms of ADAMTS13 regulation
por: DeYoung, Veronica, et al.
Publicado: (2022)

von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice
por: Portier, Irina, et al.
Publicado: (2018)

Biventricular Remodeling in Murine Models of Right Ventricular Pressure Overload
por: Kapur, Navin K., et al.
Publicado: (2013)

Cardiomyocyte ZKSCAN3 regulates remodeling following pressure‐overload
por: Ouyang, Xiaosen, et al.
Publicado: (2023)

Androgens Contribute to Sex Differences in Myocardial Remodeling under Pressure Overload by a Mechanism Involving TGF-β
por: Montalvo, Cecilia, et al.
Publicado: (2012)

ADAMTS Proteins and Vascular Remodeling in Aortic Aneurysms
por: Mougin, Zakaria, et al.
Publicado: (2021)

Association between plasma ADAMTS-7 levels and ventricular remodeling in patients with acute myocardial infarction
por: Wu, Wenjing, et al.
Publicado: (2015)

Generation and validation of small ADAMTS13 fragments for epitope mapping of anti‐ADAMTS13 autoantibodies in immune‐mediated thrombotic thrombocytopenic purpura
por: Kangro, Kadri, et al.
Publicado: (2020)

Temperature‐dependent irreversible conformational change of recombinant ADAMTS13 upon metal ion chelation
por: Rottensteiner, Hanspeter, et al.
Publicado: (2019)

Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease
por: Rossato, Paolo, et al.
Publicado: (2022)

Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model
por: Kraisin, Sirima, et al.
Publicado: (2014)

Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling
por: Kojonazarov, Baktybek, et al.
Publicado: (2013)

Pressure-overload-induced angiotensin-mediated early remodeling in mouse heart
por: Kim, Jeremy H., et al.
Publicado: (2017)

Innate Immune Cells in Pressure Overload-Induced Cardiac Hypertrophy and Remodeling
por: Liu, Xin, et al.
Publicado: (2021)

Mitophagy: A Potential Target for Pressure Overload-Induced Cardiac Remodelling
por: Shao, Ruochen, et al.
Publicado: (2022)

Frequency of Pro475Ser Polymorphism of ADAMTS13 Gene and Its Association with ADAMTS-13 Activity in the Korean Population
por: Jang, Mun Ju, et al.
Publicado: (2008)

ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome-PTEN-mTOR-autophagy pathway
por: Han, Xiao, et al.
Publicado: (2022)

Association of serum ADAMTS-7 levels with left ventricular reverse remodeling after ST-elevation myocardial infarction
por: Wu, Wenjing, et al.
Publicado: (2018)

Pressure Overload-induced Cardiac Remodeling and Dysfunction in the Absence of Interleukin 6 in Mice
por: Lai, N. Chin, et al.
Publicado: (2012)

Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure
por: Patel, Bindiya, et al.
Publicado: (2017)

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice
por: Wang, Qiancheng, et al.
Publicado: (2017)

Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload
por: Jung, Hanna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vdbd497hr4gjrf7nj8ugcv1hi9