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Liver X Receptor–Binding DNA Motif Associated With Atherosclerosis‐Specific DNA Methylation Profiles of Alu Elements and Neighboring CpG Islands

BACKGROUND: The signals that determine atherosclerosis‐specific DNA methylation profiles are only partially known. We previously identified a 29‐bp DNA motif (differential methylation motif [DMM]) proximal to CpG islands (CGIs) that undergo demethylation in advanced human atheromas. Those data hinte...

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Detalles Bibliográficos
Autores principales: Tristán‐Flores, Fabiola E., Guzmán, Plinio, Ortega‐Kermedy, Melany S., Cruz‐Torres, Gabriela, de la Rocha, Carmen, Silva‐Martínez, Guillermo A., Rodríguez‐Ríos, Dalia, Alvarado‐Caudillo, Yolanda, Barbosa‐Sabanero, Gloria, Sayols, Sergi, Lund, Gertrud, Zaina, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850253/
https://www.ncbi.nlm.nih.gov/pubmed/29386205
http://dx.doi.org/10.1161/JAHA.117.007686