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Evidence for the Selective Basis of Transition-to-Transversion Substitution Bias in Two RNA Viruses

The substitution rates of transitions are higher than expected by chance relative to those of transversions. Many have argued that selection disfavors transversions, as nonsynonymous transversions are less likely to conserve biochemical properties of the original amino acid. Only recently has it bec...

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Detalles Bibliográficos
Autores principales: Lyons, Daniel M, Lauring, Adam S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850290/
https://www.ncbi.nlm.nih.gov/pubmed/29029187
http://dx.doi.org/10.1093/molbev/msx251