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Evolution of Local Mutation Rate and Its Determinants

Mutation rate varies along the human genome, and part of this variation is explainable by measurable local properties of the DNA molecule. Moreover, mutation rates differ between orthologous genomic regions of different species, but the drivers of this change are unclear. Here, we use data on human...

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Detalles Bibliográficos
Autores principales: Terekhanova, Nadezhda V., Seplyarskiy, Vladimir B., Soldatov, Ruslan A., Bazykin, Georgii A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850301/
https://www.ncbi.nlm.nih.gov/pubmed/28138076
http://dx.doi.org/10.1093/molbev/msx060