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Complex CatSper-dependent and independent [Ca(2+)](i) signalling in human spermatozoa induced by follicular fluid

STUDY QUESTION: Does progesterone in human follicular fluid (hFF) activate CatSper and do other components of hFF modulate this effect and/or contribute separately to hFF-induced Ca(2+) signaling? SUMMARY ANSWER: hFF potently stimulates CatSper and increases [Ca(2+)](i), primarily due to high concen...

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Detalles Bibliográficos
Autores principales: Brown, Sean G., Costello, Sarah, Kelly, Mark C., Ramalingam, Mythili, Drew, Ellen, Publicover, Stephen J., Barratt, Christopher L.R., Da Silva, Sarah Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850303/
https://www.ncbi.nlm.nih.gov/pubmed/28938737
http://dx.doi.org/10.1093/humrep/dex269