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Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria

The fitness effects of mutations can depend on the genetic backgrounds in which they occur and thereby influence future opportunities for evolving populations. In particular, mutations that fix in a population might change the selective benefit of subsequent mutations, giving rise to historical cont...

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Detalles Bibliográficos
Autores principales: Peng, Fen, Widmann, Scott, Wünsche, Andrea, Duan, Kristina, Donovan, Katherine A, Dobson, Renwick C J, Lenski, Richard E, Cooper, Tim F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850340/
https://www.ncbi.nlm.nih.gov/pubmed/29069429
http://dx.doi.org/10.1093/molbev/msx279