Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA copy according to Watson-Crick base-pairing ru...

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Detalles Bibliográficos
Autores principales: Selisko, Barbara, Papageorgiou, Nicolas, Ferron, François, Canard, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850366/
https://www.ncbi.nlm.nih.gov/pubmed/29385764
http://dx.doi.org/10.3390/v10020059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850366/
https://www.ncbi.nlm.nih.gov/pubmed/29385764
http://dx.doi.org/10.3390/v10020059

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