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Mosaic Brain Aneuploidy in Mental Illnesses: An Association of Low-level Post-zygotic Aneuploidy with Schizophrenia and Comorbid Psychiatric Disorders

BACKGROUND: Postzygotic chromosomal variation in neuronal cells is hypothesized to make a substantial contribution to the etiology and pathogenesis of neuropsychiatric disorders. However, the role of somatic genome instability and mosaic genome variations in common mental illnesses is a matter of co...

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Detalles Bibliográficos
Autores principales: Yurov, Yuri B., Vorsanova, Svetlana G., Demidova, Irina A., Kolotii, Alexei D., Soloviev, Ilia V., Iourov, Ivan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850504/
https://www.ncbi.nlm.nih.gov/pubmed/29606903
http://dx.doi.org/10.2174/1389202918666170717154340