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Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation

One of the most abundant proteins in human saliva, mucin-7, is encoded by the MUC7 gene, which harbors copy number variable subexonic repeats (PTS-repeats) that affect the size and glycosylation potential of this protein. We recently documented the adaptive evolution of MUC7 subexonic copy number va...

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Detalles Bibliográficos
Autores principales: Xu, Duo, Pavlidis, Pavlos, Taskent, Recep Ozgur, Alachiotis, Nikolaos, Flanagan, Colin, DeGiorgio, Michael, Blekhman, Ran, Ruhl, Stefan, Gokcumen, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850612/
https://www.ncbi.nlm.nih.gov/pubmed/28957509
http://dx.doi.org/10.1093/molbev/msx206