Progress in the Fight Against Multidrug-Resistant Bacteria 2005–2016: Modern Noninferiority Trial Designs Enable Antibiotic Development in Advance of Epidemic Bacterial Resistance

From a public health perspective, new antibacterial agents should be evaluated and approved for use before widespread resistance to existing agents emerges. However, for multidrug-resistant pathogens, demonstration of superior efficacy of a new agent over a current standard-of-care agent is routinel...

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Detalles Bibliográficos
Autores principales: Rex, John H, Talbot, George H, Goldberger, Mark J, Eisenstein, Barry I, Echols, Roger M, Tomayko, John F, Dudley, Michael N, Dane, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Viewpoints
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850636/
https://www.ncbi.nlm.nih.gov/pubmed/29017263
http://dx.doi.org/10.1093/cid/cix246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850636/
https://www.ncbi.nlm.nih.gov/pubmed/29017263
http://dx.doi.org/10.1093/cid/cix246

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