Inhibition of TRPA1 Attenuates Doxorubicin-Induced Acute Cardiotoxicity by Suppressing Oxidative Stress, the Inflammatory Response, and Endoplasmic Reticulum Stress

The transient receptor potential ankyrin 1 (TRPA1) channel is expressed in cardiomyocytes and involved in many cardiovascular diseases. However, the expression and function of TRPA1 in doxorubicin- (Dox-) induced acute cardiotoxicity have not been elucidated. This study aimed at investigating whethe...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Wang, Menglong, Liu, Jianfang, Ye, Jing, Jiang, Huimin, Xu, Yao, Ye, Di, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850896/
https://www.ncbi.nlm.nih.gov/pubmed/29682158
http://dx.doi.org/10.1155/2018/5179468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850896/
https://www.ncbi.nlm.nih.gov/pubmed/29682158
http://dx.doi.org/10.1155/2018/5179468

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