Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

BACKGROUND: Type 2 diabetes (T2D) is a risk factor for the development of tuberculosis (TB), although the associated mechanisms are not known. OBJECTIVES: To study the association between T2D and the basal phenotype of macrophages, and their immune response to Mycobacterium tuberculosis (Mtb) infect...

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Detalles Bibliográficos
Autores principales: Lopez-Lopez, Nallely, Martinez, Ana Gabriela Ramos, Garcia-Hernandez, Mariana Haydee, Hernandez-Pando, Rogelio, Castañeda-Delgado, Julio Enrique, Lugo-Villarino, Geanncarlo, Cougoule, Céline, Neyrolles, Olivier, Rivas-Santiago, Bruno, Valtierra-Alvarado, Monica Alejandra, Rubio-Caceres, Marisela, Enciso-Moreno, Jose Antonio, Serrano, Carmen Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851047/
https://www.ncbi.nlm.nih.gov/pubmed/29513874
http://dx.doi.org/10.1590/0074-02760170326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851047/
https://www.ncbi.nlm.nih.gov/pubmed/29513874
http://dx.doi.org/10.1590/0074-02760170326

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