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RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells
BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly characterized by retinal pigment epithelium (RPE) degeneration with accumulation of abnormal intracellular deposits (lipofuscin) and photoreceptor death. RPE is vital for the retina and integrity of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851074/ https://www.ncbi.nlm.nih.gov/pubmed/29534722 http://dx.doi.org/10.1186/s12967-018-1434-6 |