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RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells

BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly characterized by retinal pigment epithelium (RPE) degeneration with accumulation of abnormal intracellular deposits (lipofuscin) and photoreceptor death. RPE is vital for the retina and integrity of...

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Detalles Bibliográficos
Autores principales: Inana, George, Murat, Christopher, An, Weijun, Yao, Xiang, Harris, Ian R., Cao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851074/
https://www.ncbi.nlm.nih.gov/pubmed/29534722
http://dx.doi.org/10.1186/s12967-018-1434-6