Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry

Recent work using micro-Fourier transform infrared (μFTIR) imaging has revealed that a lipid-rich layer surrounds many plaques in post-mortem Alzheimer's brain. However, the origin of this lipid layer is not known, nor is its role in the pathogenesis of Alzheimer's disease (AD). Here, we s...

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Detalles Bibliográficos
Autores principales: Palombo, Francesca, Tamagnini, Francesco, Jeynes, J. Charles G., Mattana, Sara, Swift, Imogen, Nallala, Jayakrupakar, Hancock, Jane, Brown, Jonathan T., Randall, Andrew D., Stone, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851084/
https://www.ncbi.nlm.nih.gov/pubmed/29230441
http://dx.doi.org/10.1039/c7an01747b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851084/
https://www.ncbi.nlm.nih.gov/pubmed/29230441
http://dx.doi.org/10.1039/c7an01747b

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