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Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway

BACKGROUND: To investigate the treatment effect of vasoactive intestinal peptide (VIP) on osteoarthritis (OA) and the relative mechanism. METHOD: The OA model on the SD rat knee was established using the modified Hulth method, and the recombinant pcDNA3.1+/VIP plasmid was constructed. One month afte...

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Detalles Bibliográficos
Autores principales: Liang, Yaozhong, Chen, Shu, Yang, Yuhao, Lan, Chunhai, Zhang, Guowei, Ji, Zhisheng, Lin, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851098/
https://www.ncbi.nlm.nih.gov/pubmed/29540226
http://dx.doi.org/10.1186/s12929-018-0410-z