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Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia
High-grade gliomas (HGGs) include the most common and the most aggressive primary brain tumor of adults and children. Despite multimodality treatment, most high-grade gliomas eventually recur and are ultimately incurable. Several studies suggest that the initiation, progression, and recurrence of gl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851110/ https://www.ncbi.nlm.nih.gov/pubmed/29155422 http://dx.doi.org/10.1038/onc.2017.404 |