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Targeting NMDA receptors in stroke: new hope in neuroprotection

NMDA (N-methyl-d-aspartate) receptors (NMDARs) play a central role in excitotoxic neuronal death caused by ischemic stroke, but NMDAR channel blockers have failed to be translated into clinical stroke treatments. However, recent research on NMDAR-associated signaling complexes has identified importa...

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Detalles Bibliográficos
Autores principales: Wu, Qiu Jing, Tymianski, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851248/
https://www.ncbi.nlm.nih.gov/pubmed/29534733
http://dx.doi.org/10.1186/s13041-018-0357-8