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Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes

BACKGROUND/OBJECTIVES: Endocannabinoids (ECs) are associated with obesity and ectopic fat accumulation, both of which play a role in the development of cardiovascular disease (CVD) in type 2 diabetes (T2D). The effect of prolonged caloric restriction on ECs in relation to fat distribution and cardia...

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Detalles Bibliográficos
Autores principales: van Eyk, Huub J., van Schinkel, Linda D., Kantae, Vasudev, Dronkers, Charlotte E. A., Westenberg, Jos J. M., de Roos, Albert, Lamb, Hildo J., Jukema, J. Wouter, Harms, Amy C., Hankemeier, Thomas, van der Stelt, Mario, Jazet, Ingrid M., Rensen, Patrick C. N., Smit, Johannes W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851430/
https://www.ncbi.nlm.nih.gov/pubmed/29343706
http://dx.doi.org/10.1038/s41387-017-0016-7