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Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes
BACKGROUND/OBJECTIVES: Endocannabinoids (ECs) are associated with obesity and ectopic fat accumulation, both of which play a role in the development of cardiovascular disease (CVD) in type 2 diabetes (T2D). The effect of prolonged caloric restriction on ECs in relation to fat distribution and cardia...
Autores principales: | van Eyk, Huub J., van Schinkel, Linda D., Kantae, Vasudev, Dronkers, Charlotte E. A., Westenberg, Jos J. M., de Roos, Albert, Lamb, Hildo J., Jukema, J. Wouter, Harms, Amy C., Hankemeier, Thomas, van der Stelt, Mario, Jazet, Ingrid M., Rensen, Patrick C. N., Smit, Johannes W. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851430/ https://www.ncbi.nlm.nih.gov/pubmed/29343706 http://dx.doi.org/10.1038/s41387-017-0016-7 |
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