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Mycophenolic acid induces senescence of vascular precursor cells

OBJECTIVE: Endothelial dysfunction is central to the pathogenesis of many rheumatic diseases, typified by vascular inflammation and damage. Immunosuppressive drugs induce disease remission and lead to improved patient survival. However, there remains a higher incidence of cardiovascular disease in t...

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Detalles Bibliográficos
Autores principales: Go, Ellen, Tarnawsky, Stefan P., Shelley, W. Chris, Banno, Kimihiko, Lin, Yang, Gil, Chang-Hyun, Blue, Emily K., Haneline, Laura S., O’Neil, Kathleen M., Yoder, Mervin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851606/
https://www.ncbi.nlm.nih.gov/pubmed/29538431
http://dx.doi.org/10.1371/journal.pone.0193749