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Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors

Bacterial protein synthesis is intricately connected to metabolic rate. One of the ways in which bacteria respond to environmental stress is through posttranslational modifications of translation factors. Translation elongation factor Tu (EF-Tu) is methylated and phosphorylated in response to nutrie...

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Detalles Bibliográficos
Autores principales: Talavera, Ariel, Hendrix, Jelle, Versées, Wim, Jurėnas, Dukas, Van Nerom, Katleen, Vandenberk, Niels, Singh, Ranjan Kumar, Konijnenberg, Albert, De Gieter, Steven, Castro-Roa, Daniel, Barth, Anders, De Greve, Henri, Sobott, Frank, Hofkens, Johan, Zenkin, Nikolay, Loris, Remy, Garcia-Pino, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851678/
https://www.ncbi.nlm.nih.gov/pubmed/29546243
http://dx.doi.org/10.1126/sciadv.aap9714