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Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies

Endothelin-1 (ET-1), a potent vasoconstrictor normally active in maintaining vascular tone, may mediate significant pathogenic effects, contributing to several serious diseases when aberrantly expressed or regulated. The present study evaluates the capacity of ET-1 to affect endothelin-1-associated...

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Detalles Bibliográficos
Autores principales: Barta, Tunde, Tosaki, Agnes, Haines, David, Balla, Gyorgy, Lekli, Istvan, Tosaki, Arpad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851684/
https://www.ncbi.nlm.nih.gov/pubmed/29354880
http://dx.doi.org/10.1007/s00210-018-1462-z