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Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies
Endothelin-1 (ET-1), a potent vasoconstrictor normally active in maintaining vascular tone, may mediate significant pathogenic effects, contributing to several serious diseases when aberrantly expressed or regulated. The present study evaluates the capacity of ET-1 to affect endothelin-1-associated...
Autores principales: | Barta, Tunde, Tosaki, Agnes, Haines, David, Balla, Gyorgy, Lekli, Istvan, Tosaki, Arpad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851684/ https://www.ncbi.nlm.nih.gov/pubmed/29354880 http://dx.doi.org/10.1007/s00210-018-1462-z |
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