Impact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation

AIMS: Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) in T2DM patients randomly s...

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Detalles Bibliográficos
Autores principales: Bo, Simona, Togliatto, Gabriele, Gambino, Roberto, Ponzo, Valentina, Lombardo, Giusy, Rosato, Rosalba, Cassader, Maurizio, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851693/
https://www.ncbi.nlm.nih.gov/pubmed/29330620
http://dx.doi.org/10.1007/s00592-017-1097-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851693/
https://www.ncbi.nlm.nih.gov/pubmed/29330620
http://dx.doi.org/10.1007/s00592-017-1097-4

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