Cargando…

TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes

Collagen export from the endoplasmic reticulum (ER) requires TANGO1, COPII coats, and retrograde fusion of ERGIC membranes. How do these components come together to produce a transport carrier commensurate with the bulky cargo collagen? TANGO1 is known to form a ring that corrals COPII coats, and we...

Descripción completa

Detalles Bibliográficos
Autores principales: Raote, Ishier, Ortega-Bellido, Maria, Santos, António JM, Foresti, Ombretta, Zhang, Chong, Garcia-Parajo, Maria F, Campelo, Felix, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851698/
https://www.ncbi.nlm.nih.gov/pubmed/29513218
http://dx.doi.org/10.7554/eLife.32723