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The integrated landscape of causal genes and pathways in schizophrenia

Genome-wide association studies (GWAS) have identified more than 100 loci that show robust association with schizophrenia risk. However, due to the complexity of linkage disequilibrium and gene regulatory, it is challenging to pinpoint the causal genes at the risk loci and translate the genetic find...

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Detalles Bibliográficos
Autores principales: Ma, Changguo, Gu, Chunjie, Huo, Yongxia, Li, Xiaoyan, Luo, Xiong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851982/
https://www.ncbi.nlm.nih.gov/pubmed/29540662
http://dx.doi.org/10.1038/s41398-018-0114-x