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miR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy

MicroRNAs (miRNAs) are known to contribute to many metabolic diseases, including diabetes. In this study, we investigated the role of miR199a-5p in the regulation of hepatic insulin sensitivity. Ad-anti-miR199a-5p adenoviruses were injected into male C57BL/6J WT mice fed a high-fat diet to inhibit m...

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Detalles Bibliográficos
Autores principales: Li, Bo, Wu, Xiangsong, Chen, Hanbei, Zhuang, Chengle, Zhang, Zhiguo, Yao, Shuangshuang, Cai, Dongsheng, Ning, Guang, Su, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851987/
https://www.ncbi.nlm.nih.gov/pubmed/29540751
http://dx.doi.org/10.1038/s41419-018-0439-7